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Abstract
Two new triucallane triterpenoids, polystanin F (1) and polystanin G (2), along with eight known compounds (3-10) were isolated from the fruits of Aphanamixis polystachya. Their structures were established on the basis of extensive spectroscopic analysis. Moreover, eight compounds were evaluated for their in vitro cytotoxicity against three cancer cell lines (liver cancer RT112, colon cancer HCT-116 and breast cancer M231) using the MTT method. Compound 7 showed significant cytotoxic activity against HCT-116 with IC50 1.27 μM.
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Disclosure statement
No potential conflict of interest was reported by the authors.
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Funding
This work was financially supported by grants from National Natural Science Foundation of China (31760100, 31860092); Yunnan Province Natural Science Foundation (202101AT070254, 202002AA100007, 2018FF001-015).