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Abstract
One new ionone glycoside, named centrantheroside F (1), together with 9 known compounds (2-10), were isolated from the roots of Centranthera grandiflora. Their structures were determined by spectroscopic data analyses and comparing with the literature data. The absolute configuration of 1 was confirmed via 2 D NMR and electronic circular dichroism (ECD). All isolated compounds were evaluated for their inhibitory activity on lipopolysaccharide (LPS)-induced nitric oxide (NO) production.
Graphical Abstract
Acknowledgments
Authors thank Advanced Analysis and Measurement Center of Yunnan University for the sample testing service.
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was financially supported by the National Natural Science Foundation of China (21762048, 81860615, and 81903541), Applied Basic Research Foundation of Yunnan Province (2018FY001 and 2018FA048), the Open Fund of the Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Shenzhen University School of Medicine (2019B030301009-010), the Program for Changjiang Scholars and Innovative Research Team in University (IRT_17R94), Project of Innovative Research Team of Yunnan Province (202005AE160005), and Yun Ling Scholar Project to Wei-Lie Xiao.