Isolation of a new steroid from phytochemical investigation on Caralluma lasiantha

Abstract

A new steroid (acylated C₂₁ pregnane steroid) was isolated from chloroform extract in phytochemical screening of Caralluma lasiantha. The isolated compound is found to be 3β-hydroxy-14β–(6′- carboxyphenyl)propionyloxypregn–5-en-20-one based on spectroscopic studies (IR, ¹H NMR, ¹³C NMR, DEPT, COSY, HSQC, HMBC and ESI-MS). The isolated new steroid was tested against four bacterial strains and the activity was related to the structure of the molecule.

Graphical Abstract

Keywords:

• Asclepiadaceae
• Caralluma lasiantha
• Indian traditional medicine
• C₃₁ pregnane steroid
• chloroform extract
• phytochemical screening

Acknowledgements

Authors are thankful to Vignan’s Foundation for Science, Technology and Research (Deemed to be) University for providing necessary research facilities.

Disclosure statement

No potential conflict of interest was reported by the authors.