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Abstract
Two new aspidosperma-type monoterpenoid indole alkaloids, 16-O-methylvoafinine (1) and 14,15-diepi-voafinidine (2) were isolated from the aerial parts of Ervatamia officinalis. Their structures were established by comprehensive spectroscopic analysis including 1D and 2D NMR, HR-ESI-MS, and electronic circular dichroism calculation. The isolated compounds were evaluated for cytotoxic activities against HepG2, MCF-7, and A549 cell lines by CCK-8 assay.
Graphical Abstract
Disclosure statement
The authors declare no conflict of interest.
Additional information
Funding
This work was financially supported by the National Natural Science Foundation of China (No. 81803398, U1801287), Applied Basic Research Foundation of Yunnan Province (No. 2019FB117), and the Science and Technology Planning Project of Guangdong Province (No. 2020B1111110004, 2019A1515010688), and the Science and Technology Planning Project of Guangzhou City (No. 20212210005).