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Abstract
A new alkaloid (3), together with three known compounds, were isolated from the Thespesia populnea endophytic fungus TM-Y1-1. Their structures were elucidated by extensive spectroscopic methods. The absolute configuration of compound 3 was determined for the first time by ECD calculation and DP4+ analysis. All compounds were evaluated for antimicrobial activity. The results showed that compounds 1 and 2 both exhibited moderate inhibitory activity against banana Colletotrichum gloeosporioides with MIC value of 31.25 μg/ml.
Graphical Abstract
Acknowledgment
The authors gratefully acknowledge the grants from National Natural Science Foundation of China.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
The authors received grants from National Natural Science Foundation of China [No. 41876153] and Guangdong Marine Economy Development Special Project [No. GDNRC[2022]35].