https://orcid.org/0000-0001-6171-2552
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Abstract
One new lignan, julibrissinoside II, along with thirteen known compounds, was isolated from the stem bark of Albizia julibrissin. The structure of julibrissinoside II was determined on the basis of extensive spectroscopic methods, including NMR and CD spectroscopic data. The isolated compounds were tested for their SREBP-1c inhibitory activity at different concentrations using mouse hepatocyte AML12 cell lines. Among them, linoleic acid (2) and 3-O-methylfisetin (4) showed significant SREBP-1c inhibitory activity at the concentration of 100 µM.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This study was financially supported by the National Research Foundation of Korea (NRF) [2020R1A2C1012632].