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Abstract
Two new compounds, including a norsesquiterpenoid, annuionone H (1), and a quassinoid, picraqualide G (2), along with eleven known compounds (3–13), were isolated from the twigs and leaves of Picrasma quassioides. Comprehensive spectroscopic analyses and NMR calculation with DP4+ analysis were used to identify their structures. Moreover, of all these compounds, compound 4 showed a week inhibition rate in the anti-inflammatory screening results against mouse macrophage J774A.1 cell.
Graphical Abstract
Acknowledgments
Authors thank Advanced Analysis and Measurement Center of Yunnan University for the sample testing service.
Disclosure statement
The authors did not report any competing financial interests.
Additional information
Funding
This work was financially supported by the National Natural Science Foundation of China [21762048, 81860615, 81903541 and 22167021], Applied Basic Research Foundation of Yunnan Province [2018FY001, 2018FA048, 202101AS070022 and 202101AT070195], the Program for Changjiang Scholars and Innovative Research Team in University [IRT_17R94], Project of Innovative Research Team of Yunnan Province [202005AE160005], and Yun Ling Scholar Project to Wei-Lie Xiao, National Key R&D Program of China [2019YFE0109200], and a grant [no. 2021KF004] from YNCUB.