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Research Articles

Celochalcoside, a new quinochalcone C-glycoside from Celosia trigyna

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Pages 644-651 | Received 18 Mar 2023, Accepted 07 Oct 2023, Published online: 16 Oct 2023
 

Abstract

A new quinochalcone C-glycoside featuring a unique quinonoid moiety, named celochalcoside (1), was isolated from the n-butanol extract of the aerial parts of Celosia trigyna L. The structure was determined by extensive spectroscopic analysis as well as mass spectrometric data. Compound 1 showed moderate cytotoxic activities against breast cancer cell lines (MCF-7), colon cancer cell lines (HT-29) and hepatocellular carcinoma cell lines (HepG2) with IC50 values of 23.16, 37.05 and 18.35 μg/ml, respectively.

Acknowledgements

The author would like to thank Professor Wael Taha Kasem, College of Science, Al-Azhar University, Cairo, Egypt for collection and identification of the plant sample.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.

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