https://orcid.org/0000-0003-1178-0121
![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Abstract
Five new sesquiterpenoids, including a campherenane-type (1), a bergamotane-type (2), a drimane-type (3), and two bisabolane-type (5-6) sesquiterpenoids have been isolated from Biscogniauxia sp. 71-10-1-1. Their structures were determined by spectroscopic analyses, quantum chemical ECD calculations,13C chemical shifts calculations, and X-ray crystallography. This is the first report of campherenane-type and drimane-type sesquiterpenoids from Biscogniauxia. Furthermore, the anti-inflammatory assays of all compounds are evaluated, and the results showed that compounds 3 and 7 exhibited the effects against the production of the pro-inflammatory cytokine TNF-α.
Disclosure statement
The authors declare no competing financial interest.
Additional information
Funding
This work was financially supported by grants from the National Key Research and Development Program of China (2018YFA0903200/2018YFA0903201), National Natural Science Foundation of China (81925037, 82321004, 82374016, 81803408), Guangdong Major Project of Basic and Applied Basic Research (2023B0303000026), Guangdong Natural Science Funds for Distinguished Young Scholar (2017A03036027), Guangdong International Science and Technology Cooperation Base (2021A0505020015), Innovative and Research Teams Project of Guangdong Higher Education Institution (2021KCXTD001), Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (2017BT01Y036), Pearl River Nova Program of Guangzhou (201610010021), the 111 Project of Ministry of Education of China(B13038), Natural Science Foundation of Guangdong Province (2022A1515012041), Guangzhou Basic and Applied Basic Research Foundation (Doctor Young Scientific and Technical Personnel Category) (202102020849), the Science and Technology Planning Projectof Guangzhou(202201020048), and the Fundamental Research Funds for the Central Universities (21623225).