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Research Articles

Two new sesquiterpenoid glycoside compounds from the calyces of Physalis alkekengi L. var. franchetii (Mast.) Makino

ORCID Icon, , , , ORCID Icon &
Pages 795-802 | Received 26 Oct 2023, Accepted 21 Feb 2024, Published online: 21 Mar 2024
 

Abstract

Two new sesquiterpenoid glycosides, 8α (H)-eudesmane-1,3,11 (13)-triene-2-one -12-O-β-D-glucopyranoside (1) and dmetelisproside B (2), together with ten known compounds (312) were isolated from calyces of Physalis alkekengi L. var. franchetii (Mast.) Makino (PAF). Their structures were unambiguously elucidated through HR-ESI-MS, UV, IR, and NMR spectral data. Compounds 1, 10, and 12 exhibited DPPH scavenging ability with IC50 values of 33.69 ± 6.65, 6.29 ± 0.06, and 25.66 ± 3.06 μM, respectively. Additionally, 10 and 12 demonstrated weak α-glucosidase inhibition activity with IC50 values of 250.9 ± 6.60 and 347.6 ± 2.48 μM, respectively.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by the Natural Science Foundation of Heilongjiang Province (NO. YQ2019B008), Basic Scientific Research Foundation of the Higher Education Institutions of Heilongjiang Province, China (NO. 2022KYYWF0633), Heilongjiang Province Postdoctoral Science Foundation, China (NO. LBHZ20202) and North Medicine and Functional Food Characteristic Subject Project in Heilongjiang Province (No. HLJTSXK-2022-03).

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