54
Views
0
CrossRef citations to date
0
Altmetric
Notes

Triterpenoid saponins from Bupleurum marginatum and their anti-liver fibrotic activities

, , , , &
Pages 858-864 | Received 07 Jun 2023, Accepted 25 Mar 2024, Published online: 04 Apr 2024
 

Abstract

A new triterpenoid saponin (1), along with five known compounds (2–6), was isolated from Bupleurum marginatum Wall. ex DC, of which compounds 2–4 were obtained for the first time from this plant. The structures were confirmed by the analysis of 1D, 2D NMR, and HR-ESIMS data, and comparison with previous spectral data. Anti-liver fibrotic activities of the isolates were determined as proliferation inhibition of LPS-induced activation of HSC-T6 in vitro.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

The research was financially supported by the National Natural Science Foundation of China (Grant No. 81503353) and the National Major Scientific Instruments and Equipment Development Project (Grant No. 2012YQ040140).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.