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Abstract
Four new tirucallane-type triterpenoids, polystanins H–K (1–4), were obtained from the stems and leaves of Aphanamixis polystachya. Their structures were elucidated by analysis of the spectroscopic data and comparison with literature data. Compounds 1 and 2 showed week inhibitory effects against NO production in LPS-stimulated RAW264.7 cells. All the isolates were investigated for their antifungal activities against drug-resistant Candida albicans.
Acknowledgments
We thank Dr. Zhi-Bi Zhang (Kunming Medical University) for assistance with the anti-inflammatory activity assay, and thank Prof. Rui-Rui Wang (Yunnan University of Chinese Medicine) for assistance with the antifungal activity assay.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This work was financially supported by grants from National Natural Science Foundation of China (31760100); Yunnan Province Major Science and Technology Project (202002AA100007).