https://orcid.org/0000-0003-2840-2661
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Abstract
Phytochemical investigation on the fruiting bodies of the medicinal fungus Ganoderma lingzhi led to the isolation of a new norsteroid, namely ganonorsterone A (1), together with one known steroid, cyathisterol (2). The structure and absolute configuration of compound 1 were assigned by extensive analysis of MS, NMR data, and quantum-chemical calculations including electronic circular dichroism (ECD) and calculated 13C NMR-DP4+ analysis. Bioassay results showed that compound 1 displayed moderate inhibition on NO production in RAW 264.7 macrophages.
Disclosure statement
The authors declare that there is no conflict of interest.
Additional information
Funding
This work was financially supported by National Natural Science Foundation of China (No. 82003607), Joint Fund of Provincial Science and Technology Plan of Henan Province (No. 232301420094), Postdoctoral Research Funding of Henan Province (No. HN2022078), the Scientific and Technological Key Project in Henan Province (No. 232102310426), and Program for Innovative Research Team (in Science and Technology) in University of Henan Province (No. 24IRTSTHN039).