Structural Elucidations of Two Ent-Kaurane Dimers from Bulbs of Fritillaria ebeiensis var. purpurea

Ji-Zhou Wu

Yu-Ping Wen Faculty of Pharmaceutical Sciences, Tongji Medical University, Wuhan, 430030, China

Han-Li Ruan Faculty of Pharmaceutical Sciences, Tongji Medical University, Wuhan, 430030, China

Nian-Huan Yao Faculty of Pharmaceutical Sciences, Tongji Medical University, Wuhan, 430030, China

Qin-Shi Zhao Kunming Institute of Botany, The Academy of Sciences of China, Kunming, 650204, China

Han-Dong Sun Kunming Institute of Botany, The Academy of Sciences of China, Kunming, 650204, China

Chikako Morizane Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-01, Japan

Akira Iida Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-01, Japan

Tetsuro Fujita Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, 573-01, Japan

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Abstract

A novel ent-kaurane diterpenoid dimer, fritillebinide B (1) together with one known diterpenoid dimer fritillebinide A (2) were isolated from the bulbs of Fritillaria ebeiensis var. purpurea G.D. Yu et P. Li. Compound 1 has been established to be ent-3β-acetoxy-kauran-16β,17-acetal ent-16β-kauran-17(R)-aldehyde (1) by means of spectral analysis and chemical evidence.

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Structural Elucidations of Two Ent-Kaurane Dimers from Bulbs of Fritillaria ebeiensis var. purpurea

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Structural Elucidations of Two Ent-Kaurane Dimers from Bulbs of Fritillaria ebeiensis var. purpurea

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