Three New Taxane Diterpenoids from the Seeds of the Chinese Yew, Taxus Chinensis var Mairei

Qing-Wen Shi Laboratory of Applied Bioorganic Chemistry, Division of Life Science, Graduate School of Agricultural Science, Tohoku University, 1-1 Tsutsumidori-Amamiya, Aoba-ku, Sendai, 981-8555, Japan

Takayuki Oritani Laboratory of Applied Bioorganic Chemistry, Division of Life Science, Graduate School of Agricultural Science, Tohoku University, 1-1 Tsutsumidori-Amamiya, Aoba-ku, Sendai, 981-8555, Japan

Ji-Shun Gu Pharmaceutical Department, Cangzhou Health Bureau, Hebei Province, China

Qing-Zhi Meng Pharmaceutical Department, Cangzhou Health Bureau, Hebei Province, China

Ren-Lin Liu Jiangxi Forestry School, Jiangxi Province, China

Abstract

Three new taxoids were isolated from the seeds of the Chinese yew, Taxus chinensis var mairei, their structures were established as 9α,13α-diacetoxy-5α-cinnamoyloxy-11(15 → 1)-abeo-taxa-4(20), 11-diene-10β,15-diol, 2α,9α,10β-triacetoxy-taxa-4(20),11-diene-5α,13α-diol and 2α,7β,10β-triacetoxy-5α-cinnamyloxy-9α-hydroxy-taxa-4(20),11-diene-13-one on the basis of 1D, 2D NMR, and MS spectral analyses.

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Three New Taxane Diterpenoids from the Seeds of the Chinese Yew, Taxus Chinensis var Mairei

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Three New Taxane Diterpenoids from the Seeds of the Chinese Yew, Taxus Chinensis var Mairei

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