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Original Articles

Sesquiterpene Glucosides from Anti-leukotriene B4 Release Fraction of Taraxacum Officinale

, , , , , & show all
Pages 191-197 | Received 10 Apr 2000, Accepted 14 Sep 2000, Published online: 04 Oct 2006
 

Abstract

Chemical examination of the MeOH extract of the root of Taraxacum officinale, which exhibited inhibitory activity on the formation of leukotriene B4 from activated human neutrophils, has resulted in the isolation of 14-O-β-D-glucosyl-11,13-dihydro-taraxinic acid (1) and 14-O-β-D-glucosyl-taraxinic acid (2). The absolute stereostructure of 1 has been established by X-ray chrystallographic examination.

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