Three new hecogenin glycosides from fermented leaves of Agave americana

Abstract

Eight steroidal compounds, including three new hecogenin glycosides, agamenosides D–F, were isolated from the fermented leaves of Agave americana. The structures of the new steroidal saponins were elucidated by spectroscopic data and chemical methods. The activity of the isolated compounds on deformations of mycelia germinated from conidia of Pyricularia oaryzae P-2b was evaluated.

Keywords:

• Fermented leaves
• Steroidal saponins
• Agamenosides D–F

Acknowledgements

This work was financially supported by the National Natural Science Foundation of China (NSFC) (39969005). The authors are grateful to the analytical group of State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany for measurements of all spectra. We are also grateful to Professor Xingcong Li (University of Mississippi) for his help.