The active constituents from Gualou-xiebai-baijiu-tang part I: Active saponins

Two new steroidal saponins and a new triterpenoidal saponin, together with nine known steroidal saponins, were isolated from "Gualou-xiebai-baijiu-tang" consisting of Fructus trichosanthis and Bulbus allii macrostemi . The structures of the three new compounds were determined as 3- O - g - d -galactopyranosyl-hederagenin 28- O - g - d -xylopyranosyl (1 M 6)- g - d -galactopyranosyl ester ( 1 ), spirost 25(27)-ene-2 g ,3 g -diol-3- O - g - d -glucopyranosyl (1 M 2)- g - d -galactopyranoside ( 2 ) and 26- O - g - d -glucopyranosyl-22 f -hydroxy-5 g -furost-25(27)-ene-1 g ,3 g ,6 g ,26-tetraol-3- O - g - d -galactopyranoside ( 3 ), respectively, by means of chemical evidences and spectral analysis.

Keywords:

• Gualou-xiebai-baijiu-tang
• Trichosanthes Kirilowii Maxim
• Allium Macrostemon Bge
• Triterpenoidal Saponin
• Steroidal Saponins