Study of stereoselective synthesis of (±)-neocnidilide : Journal of Asian Natural Products Research: Vol 5, No 3

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Abstract

Neocnidilide 1, isolated from Apium graveleues L (Umbelliferae), has shown activity to inhibit the growth of mycotoxin-producing fungi. An efficient method for the synthesis of the racemic neocnidilide by the stereoselective reaction of hemiacetal 6 with n-BuMgBr has been developed.

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Study of stereoselective synthesis of (±)-neocnidilide

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Study of stereoselective synthesis of (±)-neocnidilide

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