Further studies on the synthesis of 7,17-Seco norditerpenoid alkaloids

Following the report on the synthesis of the 7,17-seco compounds [Wang, F.P., Yang, J.S., Chen, Q.H., Yu, L. and Li, B.G. (2000), Chem. Pharm. Bull. 48, 1912-1916], further studies on the reaction optimization for cleavage of the C(7),C(17) bond led to the 7,17-seco norditerpenoid alkaloids (e.g. 4, 9) in nearly 90% yield.

Keywords:

• Norditerpenoid Alkaloid
• 7,17- seco Norditerpenoid Alkaloid
• Fragmentation
• Biological Activity