Bioactive triterpenoids from Symplocos chinensis

Xi-Hao Li Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

Dian-Dian Shen Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

Nan Li Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

Shi-Shan Yu Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China

A new triterpenoid, 2 g ,3 g ,19 f ,24-tetrahydroxy-23-norurs-12-en-28-oic acid (4), together with three known triterpenoids 3-oxo-19 f ,23,24-trihydroxyurs-12-en-28-oic acid (1), 2 f ,3 g ,19 f ,23-tetrahydroxyurs-12-en-28-oic acid (2), 2 f ,3 f ,19 f ,23-tetrahydroxyurs-12-en-28-oic acid (3), was isolated from the roots of Symplocos chinensis. The new triterpenoid shows significant cytotoxic activity against B16 and BGC-823 cells.

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Bioactive triterpenoids from Symplocos chinensis

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