Isoginsenoside-Rh₃, a new triterpenoid saponin from the fruits of Panax ginseng C. A. Mey

Ji-Yan Wang College of Chinese Medicine Material, Jilin Agricultural University, Changchun, 130118, China; College of Chinese Pharmacy, Changchun College of Traditional Chinese Medicine, Changchun, 130021, China

Xiang-Gao Li College of Chinese Medicine Material, Jilin Agricultural University, Changchun, 130118, China

Yi-Nan Zheng College of Chinese Medicine Material, Jilin Agricultural University, Changchun, 130118, China

Xiu Wei Yang State Key Laboratory of Natural & Biomimetic Drugs, Peking University, Beijing, 100083, ChinaCorrespondence[email protected]

Abstract

A new dammarane-type triterpene monoglucoside, named isoginsenoside-Rh₃, has been isolated from the fruits of Panax ginseng C. A. Mey, together with eight known analogs, ginsenoside-Rb₁, -Rb₂, -Rc, -Rd, -Re, -Rg₁, -Rh₁, -Rh₂. On the basis of chemical and physicochemical evidence, the structure of isoginsenoside-Rh₃ has been elucidated as 3-O-β-d-glucopyranosyl-dammarane-(E)-20(22),24-diene-3β,12β-diol (1).

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Isoginsenoside-Rh₃, a new triterpenoid saponin from the fruits of Panax ginseng C. A. Mey

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Isoginsenoside-Rh3, a new triterpenoid saponin from the fruits of Panax ginseng C. A. Mey

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Isoginsenoside-Rh₃, a new triterpenoid saponin from the fruits of Panax ginseng C. A. Mey