Note: A new biologically active flavonol glycoside from Psoralea corylifolia (Linn.)

Abstract

A new biologically active flavonol glycoside (1) mp 264–265°C, C₃₂H₃₈O₂₀, [M]⁺ 742 (EIMS) has been isolated from the methanol-soluble fraction of the defatted seeds of Psoralea corylifolia (Linn.). It was characterised as the new flavonol glycoside 3,5,3′,4′-tetrahydroxy-7-methoxyflavone-3′-O-α-l-xylopyranosyl(1→3)-O-α-l-arabinopyranosyl(1→4)-O-β-d-galactopyranoside by several colour reactions, spectral analysis and chemical degradations. Compound 1 showed anti-microbial activity against various bacteria and fungi.

Keywords:

• Psoralea corylifolia (Linn.)
• Leguminosae
• Flavonoid
• Antimicrobial activity

Acknowledgements

The authors are thankful to Professor V.K. Saxena, Head, Department of Chemistry, Dr H. S. Gour University, Sagar (MP), for providing laboratory facilities, to the Head, R.S.I.C, C.D.R.I, Lucknow for spectral analysis, and to the Head, Department of Botany, Dr. H. S. Gour University, Sagar (MP) for microbial facilities.