Terpene alkaloids from Tripterygium wilfordii

Xiao-Dong Wang College of Pharmaceuticals and Biotechnology, Tianjin University, Tianjin, 300072, China

Wei Jia School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200030, China

Wen-Yuan Gao College of Pharmaceuticals and Biotechnology, Tianjin University, Tianjin, 300072, China

Rong Zhang College of Pharmaceuticals and Biotechnology, Tianjin University, Tianjin, 300072, China

Yan-Wen Zhang School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China

Jun Zhang School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China

Yoshihisa Takaishi Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima, 770-8505, Japan

Hong-Quan Duan School of Pharmacy, Tianjin Medical University, Tianjin, 300070, ChinaCorrespondence[email protected]

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Abstract

Two new sesquiterpene alkaloids, 1β-hydroxy-2β,5α,11-triacetoxy-7β-nicotinoyl-8β-benzoyl-dihydroagarofuran (1), and 1β,5α,11-triacetoxy-7β-nicotinoyl-8β-benzoyl-dihydroagarofuran (2) were isolated from the xylem of Tripterygium wilfordii, together with six known compounds. Their structures were elucidated on the basis of spectroscopic studies.

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Terpene alkaloids from Tripterygium wilfordii

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Terpene alkaloids from Tripterygium wilfordii

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