Two novel phloroglucinol derivatives from Euphorbia ebracteolata hayata

Abstract

Two new phloroglucinol derivatives, named ebracteolatain A and ebracteolatain B, along with three known phloroglucinol derivatives were isolated from Euphorbia ebracteolata Hayata., and their structures were elucidated as 3,3′-diacetyl-2,4′-dimethoxy-2′,4,6,6′-tetrahydroxy-5′-methyl diphenylmethane (1) and 1-[3,5-bis-(3-acetyl-2,6-dihydroxy-4-methoxy-benzyl)-2,4,6-trihydroxy-phenyl]-ethanone (2) on the basis of spectroscopic techniques and chemical methods.

Keywords:

• Euphorbia ebracteolata Hayata
• Euphorbi aceae
• Phloroglucinol derivatives
• Ebracteolatain A
• Ebracteolatain B

Acknowledgements

We are grateful to Dr. Qiu Shengxiang, Professor of Washington University for the measurement of part of NMR spectrum, and the members of MS measurement center of the school of China Matreia Madica, China Pharmaceutical University, Nanjing, China. This work was supported by both a grant from the State Ministry of Education (No. 02118), and a grant for outstanding scholar from Jangsu Province Government, awarded to Dr Bo-yang YU.