Thiophenes from Echinops latifolius

Abstract

Six thiophenes were isolated and purified from ethanol extract of the roots of Echinops latifolius Tausch. Their structures were identified on the basis of spectral data. Among them, 5-(3-hydroxmethyl-3-isovaleroyloxyprop-1-ynyl)-2,2′-bithiophene (6) is a new compound, and 5-(3-hydroxy-4-isovaleroyloxybut-1-ynyl)-2,2′-bithiophene (5) was isolated from this plant for the first time.

Keywords:

• Echinops latifolius
• Compositae
• Thiophenes
• 5-(3-Hydroxmethyl-3-isovaleroyloxyprop-1-ynyl)-2,2′-bithiophene

Acknowledgements

We are grateful to the Analytical Detective Center, Shenyang Pharmaceutical University, for recording MS and NMR spectra.