Flavone c-glycosides from Trollius ledebouri reichb

Abstract

A new acylated C-glycosylflavone (1) was isolated from Trollius ledebouri Reichb together with two known C-glycosyflavones (2, 3). The structures were elucidated by spectroscopic methods, including HRMS, IR, ¹H and ¹³C NMR and 2D experiments (COSY, HMQC and HMBC). The anti-inflammatory activities of 1–3 were tested on TPA-induced mice ear edema (in vivo).

Keywords:

• Trollius ledebouri Reichb
• C-glycosylflavone
• Anti-inflammation