Cimifoetisides VI and VII Two new cyclolanostanol triterpene glycosides from the aerial parts of Cimicifuga foetida

Abstract

Two new cyclolanostanol triterpene glycosides, cimifoetiside VI (1) and cimifoetiside VII (2), and one known compound were isolated from the aerial parts of Cimicifuga foetida L. On the basis of spectral and chemical evidences, the structures of 1 and 2 were elucidated to be (23R,24S)-24-O-acetylisodahurinol-3-O-β-d-galactopyranoside and (23R,24R)-24-O-acetylshengmanol-3-O-β-d-glucopyranosyl-(1″ → 2′)-β-d-xylopyranoside. The known compound was identified as (23R,24R)-24-O-acetylshengmanol-3-O-β-d-galactopyranoside (3).

Keywords:

• Cimicifuga foetida
• Ranunculaceae
• Cyclolanostanol triterpene glycosides
• Cimifoetiside VI
• Cimifoetiside VII

Acknowledgements

The authors are grateful to Dr Guangzhong Tu and Miss Dongge An, Beijing Institute of Microchemistry Research, for NMR spectral measurement; to Dr Kaihua Wei, Academy of Military Medical Sciences, Beijing Centre of Biomedical Analysis, for the FAB mass spectral measurements; and to Mr H.T. Song, Ms Qi Zhang of our Institute for the IR and optical rotation spectral measurements.