Cuneatoside, a new megastigmane diglycoside from Erythroxylum cuneatum Blume

Abstract

A new megastigmane diglycoside, inamoside 6′-O-l-α-arabinofuranoside (cuneatoside), was isolated from the leaves and branches of Erythroxylum cuneatum together with seven known compounds, (+)-catechin, quercetin 3-O-α-l-rhamnoside, apocynol B, (6S,9R)-roseoside, vomifoliol 9-O-α-l-arabinofuranosyl (1 → 6)-β-d-glucopyranoside, inamoside, and citroside A The structural elucidations were based on analyses of physical and spectroscopic data.

Keywords:

• Erythroxylum cuneatum
• Erythroxylaceae
• Megastigmane diglycoside
• Apocynol B
• Vomifoliol diglycoside
• Cuneatoside

Acknowledgements

The authors thank the Faculty of Pharmaceutical Sciences, Khon Kaen University for financial support of this work. We also thank Dr. Thaweesak Thitimetharoch of the Department of Pharmaceutical Botany and Pharmacognosy, Faculty of Pharmaceutical Sciences, Khon Kaen University, for identification of the plant.