A new sesquiterpene lactone with sulfonic acid group from Saussurea lappa

Abstract

A new sesquiterpene lactone with an unusual sulfonic acid group, 13-sulfo-dihydrodehydrocostus lactone (1), was isolated from the roots of Saussurea lappa C. (Compositae), together with a known lignan (2). The structure of 1 was characterized on the basis of spectral evidence including 2DNMR studies. Compound 2 was obtained from this plant for the first time.

Keywords:

• Saussurea lappa C
• Compositae
• Sesquiterpene lactone
• 13-Sulfo-dihydrodehydrocostus lactone

Acknowledgements

This work was supported by grants from the National Natural Science Foundation of China (No.30472138) and the 973-project (No.G1998051113) China. Thanks are due to Bin Xin, Department of Instrumental Analysis of Institute of Chemistry, Chinese Academy of Sciences, for the HRSIMS measurement.