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From the roots of Ligularia lapathifolia two new eremophilane-type sesquiterpenes have been isolated. Their structures were established as 3β-angeloyloxy-8β-hydroxy-6α,15β-epoxy-eremophil-7(11)-en-12,8α-olide (1) and 8βH-eremophil-3,7(11)-dien-12,8α (15,6α)-diolide (2) by spectroscopic methods including 2D NMR experiments.
This work was supported by the NSFC (No. 20372029 and No. 20021001) and by the Key Project of Chinese Ministry of Education (No. 104178).
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