Two new alkaloidal glycosides from the root bark of Ailanthus altissima

Abstract

Two new alkaloidal glycosides, canthin-6-one-5-o-β-d-xylopyranosyl- (1 → 6)-β-d-glucopyranoside (1) and canthin-6-one-1-o-β-d-xylopyranosyl- (1 → 6)-β-d-glucopyranoside (2) named ailantcanthinosides A and B, were isolated from the root bark of Ailanthus altissima. Their structures were elucidated by one-and two-dimensional ¹H NMR, ¹³C NMR, FAB-MS, HRESI-MS spectra and chemical methods.

Keywords:

• Ailanthus altissima (Mill.)
• Simaroubaceae
• Alkaloidal glucosides
• Ailantcanthinoside A
• Ailantcanthinoside B

Acknowledgements

The authors are grateful to Professor Ru-neng Zhao, College of Pharmacy, Lanzhou University, for his help in identification of plant material, and to the State Key Laboratory of Applied Organic Chemistry, Analysis Centre, Lanzhou University and Shanghai Institute of Organic Chemistry for measuring ¹H NMR, ¹³C NMR, 2D-NMR spectra and HRESI-MS, FAB-MS, respectively. This work was supported by the National Natural Science Foundation of China (NO.29772010) and the State Key Laboratory of Applied Organic Chemistry of Lanzhou University of China.