New flavonoids and other constituents from Lespedeza cuneata

Abstract

Two new flavonoids, 6,8,3′,4′-tetrahydroxy-2′-methoxy-7-methylisoflavanone (1) and 6,8,3′,4′-tetrahydroxy-2′-methoxy-6′-(1,1-dimethylallyl)-isoflavone (2), were isolated from the 95% ethanolic extract of the dried roots of Lespedeza cuneata together with betulinic acid (3), β-sitosterol (4), hexacosanoic acid 2,3-dihydroxy-propyl ester (5), which were isolated from this plant for the first time. Their structures were elucidated by spectral analysis.

Keywords:

• Lespedeza cuneata
• Flavonoids
• 6,8,3′,4′-Tetrahydroxy-2′-methoxy-7-methylisoflavanone
• 6,8,3′,4′-Tetrahydroxy-2′-methoxy-6′-(1,1-dimethylallyl)-isoflavone

Acknowledgements

Financial support was provided by the National Natural Sciences Foundations of China (No. 969010104). All of the spectral data were performed by the analysis centre of our institute.