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Original Articles

Antibacterial constituents from Stemona sessilifolia

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Pages 479-485 | Received 06 Jul 2006, Accepted 16 Nov 2006, Published online: 27 Jul 2010
 

Abstract

Bioassay-guided fractionation led to the isolation of eight compounds from Stemona sessilifolia. Of the eight isolates, three new bibenzyls, stilbostemins M–O (13), and a new tocopherol, 6-methoxy-3,4-dehydro-δ-tocopherol (4) were revealed together with four known compounds 3,5-dihydroxy-2′-methoxy bibenzyl (5), 3,5-dihydroxy bibenzyl (6), β-tocopherol (7), and γ-tocopherol (8). Compounds 5, 6, and 8 exhibited strong antibacterial activities against Staphylococcus aureus and S. epidermidis.

Acknowledgements

This work was supported by a grant from Hi-Tech Research and Development Program of China (2004AA2Z3302).

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