Brominated derivatives from the Chinese sponge Pseudoceratina sp.

Abstract

Chemical examination of the marine sponge Pseudoceratina sp. resulted in the isolation and characterization of two new dibromotyrosine-derived metabolites (1–2), and a new histamine-derived alkaloid (3), along with eight known dibromotyrosine based products. Their structures were elucidated on the basis of IR, 1D and 2D NMR, and MS spectral data analyses.

Keywords:

• sponge
• Pseudoceratina sp
• brominated derivatives
• alkaloid

Acknowledgements

This work was supported by grants from NSFC (No. 30672607), the National Hi-Tech Projects (2006AA09Z446, 2006DFA31100), China Uni-PhD Base Project (20060001149), and the International Cooperation Projects of “2 + 2” BMBF-MOST.