Two new triterpenoid saponins from the carpophore of Xanthoceras sorbifolia Bunge

Abstract

Two new triterpenoid saponins (1, 2) and a known sapogenin (3) were isolated from the dried carpophore of Xanthoceras sorbifolia Bunge. (Sapindaceae), and their structures were established as 3-O-β-d-glucopyranosyl, 28-O-[α-l-rhamnosyl (1 → 2)]-β-d-glucopyranosyl 16-deoxybarrin-gtogenol C (1), 3-O-[β-d-glucopyranosyl(1 → 6)] 3′-angeloyl)-β-d-glucopyranosyl, 28-O-[α-l-rhamnosyl(1 → 2)]-β-d-glucopyranosyl 16-deoxybarringtogenol C (2), 16-deoxybarringtogenol C (3), by spectral and chemical methods. Compounds 1 and 2 were found to have activity of inhibiting the proliferation of two human tumour cell lines while compound 3 was inactive.

Keywords:

• Xanthoceras sorbifolia
• Sapindaceae
• triterpenoid saponins
• cytotoxic