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Abstract
Two new lanostane triterpenoids, 29-hydroxypolyporenic acid C (4) and 25-hydroxypachymic acid (5), together with three known compounds, ergosta-7,22-dien-3β-ol (1), polyporenic acid C (2) and pachymic acid (3), were isolated from the 95% ethanolic extract of the sclerotium of Poria cocos (Schw.) Wolf. Their structures were determined by extensive spectroscopic analyses, including IR, UV, ESITOF–MS, HRESI–MS, 1D and 2D NMR data (1H NMR, 13C NMR, 1H–1H COSY, NOESY, HSQC and HMBC).
Acknowledgements
We gratefully acknowledge the National Natural Science Foundation of China (20572007), National High Technology Research and Development Programme of China (2002AA2Z343c), and Beijing Municipal Special-purpose Science Foundation of China (Z0004105040311).