One new triterpenoid from biotransformation product of glycyrrhizic acid1

1. This project was supported by the National Natural Science Foundation of China (20672142).

Abstract

A new triterpenoid compound (1) and a known compound (2) were isolated from the product of biotransformation of glycyrrhizic acid by Aspergillus niger. On the basis of the 1D and 2D NMR (¹H–¹H COSY, HSQC, HMBC and NOESY) and MS spectrometry, their structures were established as 7β, 15α-dihydroxy-3,11-dioxo-oleana-12-en-30-oic acid (1) and 15α-hydroxy-3,11-dione-oleana-12-en-30-oic acid (2), respectively.

Keywords:

• triterpenoid
• glycyrrhizic acid
• Aspergillus niger
• biotransformation

Acknowledgements

We are grateful to He-bing Chen and Yan Xue at the National Center of Biomedical Analysis for the measurements of the NMR and MS spectra.

Notes

1. This project was supported by the National Natural Science Foundation of China (20672142).

2. Tel.: [phone]. Ext. 930282. [email protected]

3. Tel.: [phone]. Ext. 930282. [email protected]

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5. Tel.: [phone]. Ext. 932247. [email protected]

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Additional information

Notes on contributors

Li-Ping Kang

2.

Jie Zhang

3.

He-Shui Yu

4.

Hong-Zhi Huang

5.

Yong-Ze Wang

6.