![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
The 60% ethanolic extract of Selaginella uncinata (Desv.) Spring possessed potent anti-anoxic effect in the anoxic PC12 cell assay. A phytochemical study of its EtOAc-soluble part led to the isolation of four new and three known biflavonoids. Their structures were established on the basis of physico-chemical properties and spectroscopic analysis. The absolute configurations of the new compounds were determined with the aid of circular dichroism (CD) spectroscopy. Compounds 4 and 5 showed potent anti-anoxic effect in the anoxic PC12 cell assay.
Acknowledgements
We are grateful to the National Basic Research Program of China for support of this research (No. 2006CB504100). Thanks are also extended to Professor Q.S. Sun (Shenyang Pharmaceutical University, Shenyang, China) for identifying the plant materials, and to Dr H. Gao, Dr X. Zhang, X. L. Wang, and J.H. Huang (Shenzhen Research Center of Traditional Chinese Medicines and Natural Products, Shenzhen, China) for measuring ESIMS and NMR measurements.