C₂₁ steroidal glycosides from Cynanchum wallichii Wight

Abstract

Three new C₂₁ steroidal glycosides, characterized with rostratamine and qinyangshengenin as aglycone moiety and 2,6-dideoxy-pyranoses as component sugars, have been isolated from the roots of Cynanchum wallichii Wight. The structures of the three new C₂₁ steroidal glycosides were elucidated as rostratamine-3-O-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-cymaropyranoside, qinyangshengenin-3-O-β-d-cymaropyranosyl-(1 → 4)-β-d-digitoxo-pyranoside, and qinyangshengenin-3-O-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-digitoxopyranoside.

Keywords:

• Cynanchum wallichii Wight
• C₂₁ steroidal glycosides
• 2,6-dideoxy-pyranoses

Acknowledgements

This research work was financially supported by the National Nature Science Foundation of China, Project No. 30672612.