Three new xanthones from the roots of Polygala japonica Houtt.

Abstract

Three new xanthones, 1,3-dihydroxy-2,5,6,7-tetramethoxyxanthone (1), 3-hydroxy-1,2,5,6,7-pentamethoxyxanthone (2), and 3,8-dihydroxy-1,2,6-trimethoxyxanthone (3), together with two known compounds were isolated from the roots of Polygala japonica Houtt. Their structures were determined on the basis of spectroscopic data.

Keywords:

• Polygala japonica Houtt.
• 1,3-dihydroxy-2,5,6,7-tetramethoxyxanthone
• 3-hydroxy-1,2,5,6,7-pentamethoxyxanthone
• 3,8-dihydroxy-1,2,6-trimethoxyxanthone

Acknowledgements

Financial support for this research was provided by the National Science Foundation of China (Nos 20372087 and 204320307). We are grateful to the Department of Instrumental Analysis, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College for all spectra measurements.