New long-chain hydroxyalkyl ferulates from the root bark of Lycium chinense Mill.

Abstract

Two new long-chain hydroxyalkyl ferulates, (E)-22-hydroxydocosyl 3-(4-hydroxy-3-methoxyphenyl)acrylate (lyciumol A, 1) and (E)-20-hydroxyeicosyl 3-(4-hydroxy-3-methoxyphenyl)acrylate (lyciumol B, 2), together with eight known compounds, were isolated from the root bark of Lycium chinense Mill. Their structures were elucidated by spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS analysis.

Keywords:

• Lycium chinense
• long-chain hydroxyalkyl ferulates
• lyciumol A
• lyciumol B

Acknowledgements

The authors thank Prof. Qin-Shi Zhao, Kunming Institute of Botany, Chinese Academy of Sciences, for his kind help. We are also thankful to the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences for recording the NMR spectra.