Two novel sesquiterpenoids from Ainsliaea fragrans Champ.

Abstract

A new sesquiterpene lactone, 3β-O-β-d-glucopyranosyl-8α-hydroxy-11α,13-dihydrozaluzanin C (1), and a novel trinorguaiane-type sesquiterpene, 4β,10α-dimethyl-1β,5α-bicycle[3,5,0]dec-6-en-4α,10β-diol (2), together with three known compounds, glucozaluzanin C (3), 11α,13-dihydrozaluzanin C (4), and 8α-hydroxy-11α,13-dihydrozaluzanin C (5), were isolated from the whole plant of Ainsliaea fragrans Champ. The structures of 1 and 2 were elucidated on the basis of detailed spectral analysis. Structures of the known compounds were identified by comparison of its spectral data with those values in the literature.

Keywords:

• Compositae
• Ainsliaea fragrans Champ.
• 3β-O-β-d-glucopyranosyl-8α-hydroxy-11α,13-dihydrozaluzanin C
• 4β,10α-dimethyl-1β,5α-bicycle[3,5,0]dec-6-en-4α,10β-diol