Two new compounds from fermentation liquid of the marine fungus Trichoderma atroviride G20-12

Abstract

The chemical constituent research on the ethyl acetate extracts of fermentation liquid of the marine fungus Trichoderma atroviride G20-12 led to the isolation of two new compounds, 2-hydroxybutan-3-yl 5′-(2″-hydroxy-N-(2‴-oxobutan-3‴-yl)propanamido)butanoate (1) and 3-hydroxy-5-(4-hydroxybenzyl)dihydrofuran-2(3H)-one (2). The structures of the new compounds were determined by spectroscopic and chemical analysis.

Keywords:

• chemical constituent
• marine fungus
• Trichoderma atroviride

Acknowledgements

This work was supported by the Ministry of Science and Technology ‘863’ project of China under Contract No. 2007AA09Z435 and the National Natural Science Foundation of China under Contract No. 40776098. The authors thank Prof. Li Tian for the cultivation and identification of the fungus.