Steroids and alkaloids from the South China Sea sponge Axinella sp.

Abstract

A new steroid 24β-methylcholasta-1,8,14,22,25-penten-3-one-5α-ol (1) and a new alkaloid 1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane (2), together with four known compounds, were isolated from the EtOH extract of the South China Sea sponge Axinella sp. The structures of 1 and 2 were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR spectral data.

Keywords:

• sponge
• Axinella sp.
• 24β-methylcholasta-1,8,14,22,25-penten-3-one-5α-ol
• 1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane
• steroid
• alkaloid