Prenylated C₆–C₃ compounds from the fruits of Illicium simonsii

Abstract

Two new prenylated C₆–C₃ compounds, 4-epi-illicinone E-12-shikimate (1) and 3-hydroxyillifunone B (2), together with five known prenylated C₆–C₃ compounds (3–7), were isolated from the fruits of Illicium simonsii. Their structures were elucidated on the basis of extensive spectroscopic methods, including 1D and 2D NMR, CD spectra, and ESI-MS analysis.

Keywords:

• Illicium simonsii
• prenylated C₆–C₃ compounds
• 4-epi-illicinone E-12-shikimate
• 3-hydroxyillifunone B

Acknowledgements

The project was supported by the National Science Fund for Distinguished Young Scholars (No. 30625040) and the National Key Basic R&D (973) Project (No. 2004CB518906). We thank the Department of Instrumental Analysis, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College for measuring the IR, NMR, MS, and CD spectra.