Two new flavan-4-ol glycosides from Abacopteris penangiana

Abstract

Two new flavan-4-ol glycosides, (2R,4S)-6,8-dimethyl-7-hydroxy-4′-methoxy-4,2″-oxidoflavan-5-O-β-d-6″-O-acetyl-glucopyranoside (1) and (2R,4S)-5,7-O-β-d-di-glucopyranosyloxy-4′-methoxy-6,8-dimethyl-4,2″-oxidoflavane (2), were isolated from the rhizomes of Abacopteris penangiana. Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 showed significant anticancer activities against HeLa and L929 cell lines in vitro.

Keywords:

• Amaranthaceae
• Abacopteris penangiana
• flavan-4-ol glycoside
• antitumor activity

Acknowledgement

This work was sponsored by the Scientific Research Foundation of Tianjin Medical University.