Structures of Two New Diterpenoid Dimers from Bulbs of Fritillaria ebeiensis

Ji-Zhou Wu

Han-Li Ruan Faculty of Pharmaceutical Sciences, Tongji Medical University, Wuhan, 430030, China

Chun-Lan Zeng Faculty of Pharmaceutical Sciences, Tongji Medical University, Wuhan, 430030, China

Hua-An Cheng Faculty of Pharmaceutical Sciences, Tongji Medical University, Wuhan, 430030, China

Fang Zhang Faculty of Pharmaceutical Sciences, Tongji Medical University, Wuhan, 430030, China

Qin-Shi Zhao Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, China

Han-Dong Sun Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, China

Tetsuro Fujita Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, 573-0101, Japan

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Abstract

Two new ent-kauranoid diterpenoid dimers, fritillebin C (1) and fritillebin D (2), were isolated from the bulbs of Fritillaria ebeiensis G.D. Yu and G.Q. Ji. Their structures were determined to be ent-16β-hydroxy-kauran-17-yl ent-16β-kauran-17-oate (1); ent-16α-hydroxy-kauran-17-yl ent-16β-kauran-17-oate (2) by means of spectral analysis and chemical evidence.

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Structures of Two New Diterpenoid Dimers from Bulbs of Fritillaria ebeiensis

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Structures of Two New Diterpenoid Dimers from Bulbs of Fritillaria ebeiensis

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