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Polycyclic Aromatic Compounds Volume 40, 2020 - Issue 5
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Articles

Synthesis of 2-Oxo-Pyridines Catalyzed by Biosynthesized CuO Nanoparticles

Javad Safaei-GhomiDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-9837-4478View further author information
ORCID Icon &
Hossein Shahbazi-AlaviDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranView further author information
Pages 1534-1538 | Received 06 Jun 2018, Accepted 11 Dec 2018, Published online: 22 Jan 2019
 
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Abstract

Nano-CuO has been used as an efficient catalyst for the preparation of pyridine derivatives by four-component reaction of hydrazine hydrate, ethyl cyanoacetate, malononitrile, and aldehydes. The present synthetic protocol provides several advantages such as simplicity of operation, wide range of products, excellent yields, short reaction times, retrievability of the catalyst, and low catalyst loading.

Acknowledgement

The authors are grateful to the University of Kashan for supporting this work.

Additional information

Funding

The authors are grateful to the University of Kashan for supporting this work.

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