Carboxymethyl Cellulose (CMC) as a Recyclable Green Catalyst Promoted Eco-Friendly Protocol for the Solvent-Free Synthesis of 1H-Pyrazolo[1,2-b]Phthalazine-5,10-Dione Derivatives

Abstract

An eco-safe synthetic route for convenient one-pot synthesizing 1H-pyrazolo[1,2-b] phthalazine-5,10-dione derivatives through Knoevenagel-Michael cyclocondensation is reported in carboxymethyl cellulose (CMC) based on green chemistry principles. The prominent benefits include use of recyclable green catalyst, commercially accessible inexpensive starting materials, operational simplicity, non-hazardous reaction circumstances, high atom-economy, solvent-free, short reaction times and high yields.

Keywords:

• 1H-pyrazolo[12-b]phthalazine-510-dione derivatives
• carboxymethyl cellulose (CMC)
• green procedure
• recyclable and biodegradable catalyst

Disclosure statement

There are no conflicts of interest.

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

We gratefully acknowledge financial support from the Research council of the Apadana Institute of Higher Education.